Back in March 2020, as the COVID-19 pandemic first swept around the world, I reviewed David Quammen’s 2012 book Spillover for background reading. It looked at the risk of zoonosis: the spilling over of an infectious disease from animal into human populations. Quammen warned, and gave voice to many others who similarly warned, that the next big disease outbreak might very well be viral, in particular RNA viruses such as coronaviruses. Other authors quickly wrote books within the first year of the pandemic (I reviewed some of them), but not yet Quammen: “early in 2021 I decided to keep quiet for a while and listen” (p. 282). Finally, in October 2022, his book Breathless provided us with his insights into COVID-19 and the virus SARS-CoV-2.