gene editing

Book review – Life as We Made It: How 50,000 Years of Human Innovation Refined – and Redefined – Nature

7-minute read

Books can be like buses: nothing is written on a topic for ages and then two books appear in quick succession. The subtitle of Life as We Made It resembles that of the recently-reviewed Life Changing. Both books indeed cover the same topic: how humans have shaped the genetics and evolution of plants and animals around them. Despite some inevitable overlap, Beth Shapiro draws on two decades of her career as a geneticist to make Life as We Made It a beast all of its own. I found myself both thoroughly enjoying her fantastic science communication while disagreeing with her outlook.

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Book review – Life Changing: How Humans Are Altering Life on Earth

7-minute read

Ever since humans appeared on the scene, we have been altering life on Earth. Where once our actions could be considered part of nature’s fabric, our influence has become outsized and our options to exercise it have multiplied. Though the subtitle of Life Changing does not make it explicit, science writer Helen Pilcher focuses on our impact on the genetics and evolution of life around us. A book that stands out for its balanced tone, it managed to surprise me more than once, despite my familiarity with the topics considered.

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Book review – Some Assembly Required: Decoding Four Billion Years of Life, from Ancient Fossils to DNA

7-minute read

The history of life is punctuated by major transitions and inventions: fish that moved onto land, reptiles that turned into birds. But how did these happen? In Some Assembly Required, Professor of Organismal Biology and Anatomy Neil Shubin provides an up-to-date and utterly engrossing account of the latest thinking on the great transformations in evolution. And he has one clue for you: nothing ever begins when you think it does…

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Book review – Hacking the Code of Life: How Gene Editing Will Rewrite Our Futures

Since being released on the world in 2012, the biotechnological tool CRISPR has been making headlines. Biologists used to rely on the relatively blunt tools of genetic modification, but this new tool is so precise and versatile that they now speak of gene editing instead. For people in a hurry, Nessa Carey here provides a primer on the powers and pitfalls of gene editing. Hacking the Code of Life is accessible to readers without much background in genetics, focusing more on the applications and the questions it raises than the nitty-gritty details of the tool itself.

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Book review – Kin: How We Came to Know Our Microbe Relatives

The problem with many history books is that they are written long after the facts, sometimes when the original protagonists are no longer alive. Historians or journalists often have no choice but to puzzle together the pieces of their story from eyewitness testimony or archival sources. Kin: How We Came to Know Our Microbe Relatives is a welcome exception to this rule. Written by emeritus microbiology professor John L. Ingraham, currently 94 years young, this book gives an intellectual history of the discipline of microbiology based on over seven decades of first-hand involvement and observation.

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Book review – Extended Heredity: A New Understanding of Inheritance and Evolution

In my recent review of She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity, I mentioned how the concept of heredity has become ever fuzzier the more we have learnt about how traits can be passed to the next generation. We have come from a very gene-centric period in biology, but biologists Russell Bonduriansky and Troy Day are ready to shake up the field. Neither a Lamarckian redux nor an attempt to downplay the importance of genes, this book successfully argues that the time has come to take into account non-genetic forms of heredity. Along the way, they provide a very interesting history lesson on how we got here in the first place.

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Book review – Lamarck’s Revenge: How Epigenetics Is Revolutionizing Our Understanding of Evolution’s Past and Present

As one of several intellectuals who wrote about evolution before Darwin, time has not been kind to the French naturalist Jean-Baptiste Lamarck (1744-1829). Reviled during his lifetime by the influential Cuvier, after his death he became best remembered, and ultimately ridiculed, for the idea that characters acquired during an organism’s lifetime are passed on to its offspring. With the rise of the modern field of epigenetics, some of his ideas are making a comeback, albeit modified and adapted for the 21st Century. Palaeontologist and astrobiologist Peter Ward would even like to go so far as to restore some honour to his name and consider epigenetics a neo-Lamarckian process.

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Book review – Blueprint: How DNA Makes Us Who We Are

When I opened this book and read its sales pitch (I paraphrase: “What if I told you of a new fortune-telling device that can predict psychological traits – it’s called the DNA revolution!”) I raised my inquisitive but sceptical eyebrow somewhat. Did I just pick up another piece of pop-psychology pulp? Oh boy, was I wrong! Behavioural geneticist Robert Plomin has written an incredibly interesting book with Blueprint, explaining how rapid advances in DNA sequencing technology are opening vast new vistas on the genetics underlying psychology. And is it ever so different, and more complex, than what hyped-up newspaper headlines have tried to sell us so far.

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Book review – Dinner with Darwin: Food, Drink, and Evolution

Who could refuse such an invitation to dinner? In fourteen short chapters, Dinner with Darwin provides a smörgåsbord of topics on the role of food in human evolution and vice versa, many of which have been covered here in recent reviews. This is Jonathan Silvertown’s fourth book with the University of Chicago Press, and based on this, I would love to read his other books as well. Care to join me at the table?

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Book review – The Tangled Tree: A Radical New History of Life

After I recently finished Carl Zimmer’s new book She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity, I noticed there was one mechanism of heredity he mentioned only ever so briefly: horizontal gene transfer. Since it does not play a large role in humans, it is understandable he left it aside. And doing it justice would have required almost another book. Luckily, science writer David Quammen is here to give us that book.

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